Guanhua Xie, Ph.D.

Affiliations: 
2010 Systems Biology and Disease University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Pathology, Anatomy Biology
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"Guanhua Xie"

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Laurie D. DeLeve grad student 2010 USC
 (Acceleration of resolution of cirrhosis by normalization of liver sinusoidal endothelial cell (LSEC) phenotype through the cGMP signaling pathway.)
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Publications

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Dalton G, Michelotti GA, Chen Y, et al. (2017) Hedgehog-Dependent yap Signaling Activates Serine Biogenesis and Glutaminolysis to Promote Hepatic Stellate Cell Transdifferentiation Gastroenterology. 152: S559
Xie G, Wang X, Liu P, et al. (2016) Distinctly altered gut microbiota in the progression of liver disease. Oncotarget
Swiderska-Syn M, Xie G, Michelotti GA, et al. (2016) Hedgehog regulates Yes-associated protein 1 in regenerating mouse liver. Hepatology (Baltimore, Md.)
Machado MV, Michelotti GA, Jewell ML, et al. (2016) Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease. Cell Death & Disease. 7: e2096
Coombes JD, Choi SS, Swiderska-Syn M, et al. (2015) Osteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis. Biochimica Et Biophysica Acta
Machado MV, Kruger L, Jewell ML, et al. (2015) Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. Digestive Diseases and Sciences
Pereira TA, Syn WK, MacHado MV, et al. (2015) Schistosome-induced cholangiocyte proliferation and osteopontin secretion correlate with fibrosis and portal hypertension in human and murine schistosomiasis mansoni. Clinical Science (London, England : 1979)
Machado MV, Michelotti GA, Pereira TA, et al. (2015) Accumulation of duct cells with activated YAP parallels fibrosis progression in NonAlcoholic Fatty Liver Disease. Journal of Hepatology
Machado MV, Michelotti GA, Xie G, et al. (2015) Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. Plos One. 10: e0127991
Karaca G, Xie G, Moylan C, et al. (2015) Role of Fn14 in acute alcoholic steatohepatitis in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G325-34
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