Joseph A. Toonen, Ph.D.
Affiliations: | 2013 | Cell Biology, Neurobiology, and Anatomy | Medical College of Wisconsin, Milwaukee, WI, United States |
Area:
Cell Biology, Genetics, Molecular BiologyGoogle:
"Joseph Toonen"Parents
Sign in to add mentor| D.J Sidjanin | grad student | 2013 | Medical College of Wisconsin | |
| (Forward and reverse genetic models of ocular development in mice.) | ||||
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| Pan Y, Hysinger JD, Barron T, et al. (2021) NF1 mutation drives neuronal activity-dependent initiation of optic glioma. Nature |
| Pan Y, Bush EC, Toonen JA, et al. (2017) Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature. Oncotarget. 8: 52474-52487 |
| Solga AC, Toonen JA, Pan Y, et al. (2017) The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation. Oncotarget |
| Walter C, Crawford L, Lai M, et al. (2017) Increased Tissue Stiffness in Tumors from Mice with Neurofibromatosis-1 Optic Glioma. Biophysical Journal. 112: 1535-1538 |
| Toonen JA, Ma Y, Gutmann DH. (2016) Defining the temporal course of murine neurofibromatosis-1 optic gliomagenesis reveals a therapeutic window to attenuate retinal dysfunction. Neuro-Oncology |
| Toonen JA, Solga AC, Ma Y, et al. (2016) Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology. The Journal of Experimental Medicine |
| Smithson LJ, Anastasaki C, Chen R, et al. (2016) Contextual signaling in cancer. Seminars in Cell & Developmental Biology |
| Toonen JA, Ronchetti A, Sidjanin DJ. (2016) A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. Plos One. 11: e0156184 |
| Toonen JA, Anastasaki C, Smithson LJ, et al. (2016) NF1 Germline Mutation Differentially Dictates Optic Glioma Formation and Growth in Neurofibromatosis-1. Human Molecular Genetics |
| Solga AC, Pong WW, Kim KY, et al. (2015) RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth. Neoplasia (New York, N.Y.). 17: 776-88 |