Ruchira Singh, Ph.D.

Affiliations: 
2008 Department of Anatomy and Physiology Kansas State University, Manhattan, KS, United States 
Area:
Animal Physiology Biology, Molecular Biology
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"Ruchira Singh"

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Philine A. Wangemann grad student 2008 Kansas State University
 (The role of free radical stress in the etiology of Pendred syndrome in a mouse model.)
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Publications

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Dalvi S, Galloway CA, Singh R. (2019) Pluripotent Stem Cells to Model Degenerative Retinal Diseases: The RPE Perspective. Advances in Experimental Medicine and Biology. 1186: 1-31
Anand-Apte B, Chao JR, Singh R, et al. (2018) Sorsby fundus dystrophy: Insights from the past and looking to the future. Journal of Neuroscience Research
Galloway CA, Dalvi S, Hung SSC, et al. (2017) Drusen in patient-derived hiPSC-RPE models of macular dystrophies. Proceedings of the National Academy of Sciences of the United States of America
Singh R, Kuai D, Guziewicz KE, et al. (2015) TAPharmacological modulation of photoreceptor outer segment degradation in a human iPS cell model of inherited macular degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy
Phillips MJ, Perez ET, Martin JM, et al. (2014) Modeling human retinal development with patient-specific induced pluripotent stem cells reveals multiple roles for visual system homeobox 2. Stem Cells (Dayton, Ohio). 32: 1480-92
Singh R, Shen W, Kuai D, et al. (2013) iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration. Human Molecular Genetics. 22: 593-607
Yamauchi D, Nakaya K, Raveendran NN, et al. (2010) Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth. Bmc Physiology. 10: 1
Wangemann P, Kim HM, Billings S, et al. (2009) Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression. American Journal of Physiology. Renal Physiology. 297: F1435-47
Singh R, Wangemann P. (2008) Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model. American Journal of Physiology. Renal Physiology. 294: F139-48
Jabba SV, Oelke A, Singh R, et al. (2006) Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model. Bmc Medicine. 4: 37
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