Isaac Mohar, Ph.D.

Affiliations: 
2008 University of Washington, Seattle, Seattle, WA 
Area:
Toxicology, Pharmacology
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"Isaac Mohar"

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Terrance J. Kavanagh grad student 2008 University of Washington
 (Gender and glutamate cysteine ligase modifier subunit expression as determinants of acetaminophen-induced liver damage in mice.)
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Brempelis KJ, Yuen SY, Schwarz N, et al. (2017) Central Role of the TIR domain-containing adaptor-inducing interferon-β (TRIF) Adaptor Protein in Murine Sterile Liver Injury. Hepatology (Baltimore, Md.)
Kyriakides M, Maitre L, Stamper BD, et al. (2016) Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer. Archives of Toxicology
Mohar I, Brempelis KJ, Murray SA, et al. (2015) Isolation of Non-parenchymal Cells from the Mouse Liver. Methods in Molecular Biology (Clifton, N.J.). 1325: 3-17
Lim J, Nakamura BN, Mohar I, et al. (2015) Glutamate cysteine ligase modifier subunit (Gclm) null mice have increased ovarian oxidative stress and accelerated age-related ovarian failure. Endocrinology. en20151206
Mohar I, Stamper BD, Rademacher PM, et al. (2014) Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6. Redox Biology. 2: 377-87
Takakusa H, Mohar I, Kavanagh TJ, et al. (2012) Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences. Biochemical and Biophysical Research Communications. 420: 54-60
Nakamura BN, Mohar I, Lawson GW, et al. (2012) Increased sensitivity to testicular toxicity of transplacental benzo[a]pyrene exposure in male glutamate cysteine ligase modifier subunit knockout (Gclm-/-) mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 227-41
Cole TB, Giordano G, Co AL, et al. (2011) Behavioral Characterization of GCLM-Knockout Mice, a Model for Enhanced Susceptibility to Oxidative Stress. Journal of Toxicology. 2011: 157687
Stamper BD, Mohar I, Kavanagh TJ, et al. (2011) Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting. Chemical Research in Toxicology. 24: 549-58
Mohar I, Botta D, White CC, et al. (2009) Glutamate cysteine ligase (GCL) transgenic and gene-targeted mice for controlling glutathione synthesis. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit6.16
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