P. Bryant Chase, Ph.D.

Affiliations: 
1988-2001 Radiology University of Washington, Seattle, Seattle, WA 
 2001- Biological Science Florida State University, Tallahassee, FL, United States 
Area:
Muscle physiology and biophysics; cell & molecular biomechanics of cardiac and skeletal muscle; bionanotechnology
Website:
http://www.bio.fsu.edu/faculty-chase.php
Google:
"P. Bryant Chase"
Bio:

1979 B.S. Biological Sciences, Rensselaer Polytechnic Institute
1981 M.S. Biological Sciences, Rensselaer Polytechnic Institute
1984 Ph.D. Biological Sciences, University of Southern California
1984-1988 Research Fellow in Radiology (postdoctoral), Brigham & Women's Hospital/Harvard Medical School
1988-2001 Research Faculty in Radiology, Adjunct in Physiology & Biophysics (1993-2001), University of Washington
2001-present Faculty in Biological Science, Florida State University

Cross-listing: Neurotree - Physiology Academic Tree

Parents

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Bernard C. Abbott grad student 1981-1984 USC (Neurotree)
Martin J. Kushmerick post-doc 1984-1988 Brigham & Women's Hospital/Harvard Medical School (Chemistry Tree)

Children

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Nicolas M. Brunet grad student 2002-2006 Florida State (Neurotree)
Brenda Schoffstall grad student 2003-2006 Florida State (Neurotree)
Nekeisha S. Sweeney grad student 2005-2007 Florida State (Neurotree)
Aya Kataoka Takeda grad student 2003-2008 Florida State (Neurotree)
Brian L. Storz grad student 2009 Florida State (Neurotree)
Campion K. Loong grad student 2012 Florida State (Neurotree)
John L. Williams grad student 2004-2012 Florida State (Neurotree)
King Pan Campion Loong grad student 2007-2012 Florida State (Neurotree)
Myriam A. Badr grad student 2008-2013 Florida State (Neurotree)
Justin R. Grubich post-doc 2002-2003 Florida State

Collaborators

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Albert M. Gordon collaborator 1988-2001 University of Washington (Neurotree)
Michael T. Butcher collaborator 2002-2006 Florida State
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Publications

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Morales PN, Coons AN, Koopman AJ, et al. (2024) Post-translational modifications of vertebrate striated muscle myosin heavy chains. Cytoskeleton (Hoboken, N.J.)
Rodriguez Garcia M, Schmeckpeper J, Landim-Vieira M, et al. (2023) Disruption of Z-Disc Function Promotes Mechanical Dysfunction in Human Myocardium: Evidence for a Dual Myofilament Modulatory Role by Alpha-Actinin 2. International Journal of Molecular Sciences. 24
Coscarella IL, Landim-Vieira M, Rastegarpouyani H, et al. (2023) Nucleus Mechanosensing in Cardiomyocytes. International Journal of Molecular Sciences. 24
Wiseman RW, Brown CM, Beck TW, et al. (2023) Creatine Kinase Equilibration and ΔG over an Extended Range of Physiological Conditions: Implications for Cellular Energetics, Signaling, and Muscle Performance. International Journal of Molecular Sciences. 24
Landim-Vieira M, Ma W, Song T, et al. (2023) Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221244120
Risi CM, Belknap B, White HD, et al. (2022) High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state. Pnas Nexus. 2: pgac298
Shi Y, Bethea JP, Hetzel-Ebben HL, et al. (2021) Mandibular muscle troponin of the Florida carpenter ant Camponotus floridanus: extending our insights into invertebrate Ca regulation. Journal of Muscle Research and Cell Motility
Marques MA, Landim-Vieira M, Moraes AH, et al. (2021) Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy. Chemical Science. 12: 7308-7323
Risi CM, Pepper I, Belknap B, et al. (2021) The structure of the native cardiac thin filament at systolic Ca levels. Proceedings of the National Academy of Sciences of the United States of America. 118
Zot HG, Chase PB, Hasbun JE, et al. (2020) Mechanical contribution to muscle thin filament activation. The Journal of Biological Chemistry
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