Jun Huang, Ph.D.
Affiliations: | 2008 | Georgia Institute of Technology, Atlanta, GA |
Area:
Cell and Molecular BiomechanicsGoogle:
"Jun Huang"Parents
Sign in to add mentorCheng Zhu | grad student | 2008 | Georgia Tech | |
(A kinetic study of the T cell recognition mechanism.) |
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Publications
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Sasmal DK, Feng W, Roy S, et al. (2019) TCR-pMHC bond conformation controls TCR ligand discrimination. Cellular & Molecular Immunology |
Acar H, Samaeekia R, Schnorenberg MR, et al. (2017) Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation. Bioconjugate Chemistry |
Hui E, Cheung J, Zhu J, et al. (2017) T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science (New York, N.Y.) |
Sasmal DK, Pulido LE, Kasal S, et al. (2016) Single-molecule fluorescence resonance energy transfer in molecular biology. Nanoscale |
Zhu C, Jiang N, Huang J, et al. (2013) Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network. Immunological Reviews. 251: 49-64 |
Huang J, Meyer C, Zhu C. (2012) T cell antigen recognition at the cell membrane. Molecular Immunology. 52: 155-64 |
Jiang N, Huang J, Edwards LJ, et al. (2011) Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination. Immunity. 34: 13-23 |
Sabatino JJ, Huang J, Zhu C, et al. (2011) High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses. The Journal of Experimental Medicine. 208: 81-90 |
Huang J, Zarnitsyna VI, Liu B, et al. (2010) The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature. 464: 932-6 |
Chen W, Zarnitsyna VI, Sarangapani KK, et al. (2008) Measuring Receptor-Ligand Binding Kinetics on Cell Surfaces: From Adhesion Frequency to Thermal Fluctuation Methods. Cellular and Molecular Bioengineering. 1: 276-288 |