Jonathan R. Silva, Ph.D.

Affiliations: 
2008 Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical Engineering
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"Jonathan Silva"

Parents

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Leslie Tung research assistant Johns Hopkins (Physics Tree)
Yoram Rudy grad student 2008 Washington University
 (Linking molecular dynamics of ion channels to the cardiac action potential: Simulations of wild type and mutant I(KS).)
Steve A. N. Goldstein post-doc 2008-2011 Chicago (Physics Tree)
Colin G. Nichols post-doc 2011-2012 Washington University (Neurotree)
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Publications

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Woodbury L, Angsutararux P, Marras M, et al. (2025) FGF12A Regulates Nav1.5 via CaM-regulated and CaM-independent Mechanisms. Biorxiv : the Preprint Server For Biology
Zhong L, Yan Z, Jiang D, et al. (2024) Targeting the I Channel PKA Phosphorylation Axis to Restore Its Function in High-Risk LQT1 Variants. Circulation Research
Hanson A, McClenaghan C, Weng KC, et al. (2024) Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations. Function (Oxford, England)
Schoening ME, Silva JR. (2024) Creating Computational Models of Ion Channel Dynamics. Methods in Molecular Biology (Clifton, N.J.). 2796: 139-156
Kang PW, Woodbury L, Angsutararux P, et al. (2023) Arrhythmia-associated calmodulin variants interact with KCNQ1 to confer aberrant membrane trafficking and function. Pnas Nexus. 2: pgad335
Lesage A, Lorenzini M, Burel S, et al. (2023) Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse. The Journal of General Physiology. 155
Hanson A, McClenaghan C, Weng KC, et al. (2023) Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations. Biorxiv : the Preprint Server For Biology
Moreno JD, Silva JR. (2023) Emerging methods to model cardiac ion channel and myocyte electrophysiology. Biophysics Reviews. 4: 011315
Angsutararux P, Dutta AK, Marras M, et al. (2023) Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors. The Journal of General Physiology. 155
Lesage A, Lorenzini M, Burel S, et al. (2023) FHF2 phosphorylation and regulation of native myocardial Na 1.5 channels. Biorxiv : the Preprint Server For Biology
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