Thomas J. O'Hara, Ph.D.
Affiliations: | 2011 | Biomedical Engineering | Washington University, Saint Louis, St. Louis, MO |
Area:
Biomedical Engineering, Biomechanics BiophysicsGoogle:
"Thomas O'Hara"Parents
Sign in to add mentor| Yoram Rudy | grad student | 2011 | Washington University | |
| (Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation, Experimental Validation and Application.) | ||||
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| Loucks AD, O'Hara T, Trayanova NA. (2018) Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An Study. Frontiers in Physiology. 9: 1737 |
| Qian F, Huang C, Lin YD, et al. (2017) Simultaneous electrical recording of cardiac electrophysiology and contraction on chip. Lab On a Chip |
| Sanchez-Alonso JL, Bhargava A, O'Hara T, et al. (2016) Microdomain-Specific Modulation of L-type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure. Circulation Research |
| Portero V, Le Scouarnec S, Es-Salah-Lamoureux Z, et al. (2016) Dysfunction of the Voltage-Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome. Journal of the American Heart Association. 5 |
| Yu JK, Boyle PM, O'Hara T, et al. (2016) Somatic Mosaicism of Novel SCN5A Mutation in Purkinje System (PS) may Underlie 2:1 Block in an Infant with Long QT Syndrome (LQTS) Biophysical Journal. 110: 527a |
| Zhang J, Sacher F, Hoffmayer K, et al. (2015) Cardiac Electrophysiological Substrate Underlying the ECG Phenotype and Electrogram Abnormalities in Brugada Syndrome Patients. Circulation. 131: 1950-9 |
| Trayanova NA, O'Hara T, Bayer JD, et al. (2012) Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. 14: v82-v89 |
| O'Hara T, Rudy Y. (2012) Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1023-30 |
| O'Hara T, Rudy Y. (2012) Arrhythmia formation in subclinical ("silent") long QT syndrome requires multiple insults: quantitative mechanistic study using the KCNQ1 mutation Q357R as example. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 275-82 |
| O'Hara T, Virág L, Varró A, et al. (2011) Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation. Plos Computational Biology. 7: e1002061 |