Kathryn A. Whitehead, Ph.D.

Affiliations: 
2012- Chemical Engineering Carnegie Mellon University, Pittsburgh, PA 
Area:
Drug Delivery, Biomaterials
Website:
whiteheadlab.cheme.cmu.edu
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"Kathryn Whitehead"

Parents

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Samir Mitragotri grad student 2007 UC Santa Barbara
 (Safe and effective methods for improving the oral delivery of macromolecules.)
Robert S. Langer post-doc 2008-2012 MIT (Chemistry Tree)

Children

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Katherine C. Fein grad student 2015- Carnegie Mellon
Christopher M. Knapp grad student 2012-2017 Carnegie Mellon
Rebecca L. Ball grad student 2013-2018 Carnegie Mellon
Lisa N. Kasiewicz grad student 2013-2018 Carnegie Mellon
Khalid A. Hajj grad student 2014-2019 Carnegie Mellon
Nicholas G. Lamson grad student 2014-2019 Carnegie Mellon
Kristina P. Friis post-doc 2017- Carnegie Mellon
Sam T. LoPresti post-doc 2018- Carnegie Mellon
Jilian R. Melamed post-doc 2018- Carnegie Mellon (Chemistry Tree)
John P Gleeson post-doc 2019- Carnegie Mellon
Ryan M. Weiss post-doc 2017-2019 Carnegie Mellon (Chemistry Tree)
BETA: Related publications

Publications

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Strelkova Petersen DM, Chaudhary N, Arral ML, et al. (2023) The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 192: 126-135
Friis KP, Gracin S, Oag S, et al. (2023) Spray dried lipid nanoparticle formulations enable intratracheal delivery of mRNA. Journal of Controlled Release : Official Journal of the Controlled Release Society. 363: 389-401
Fein KC, Arral ML, Kim JS, et al. (2023) Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation. Journal of Controlled Release : Official Journal of the Controlled Release Society
Melamed JR, Yerneni SS, Arral ML, et al. (2023) Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. Science Advances. 9: eade1444
Fein KC, Gleeson JP, Cochran K, et al. (2022) Long-term daily oral administration of intestinal permeation enhancers is safe and effective in mice. Bioengineering & Translational Medicine. 8: e10342
Doerfler R, Melamed JR, Whitehead KA. (2022) The Effect of Infant Gastric Digestion on Human Maternal Milk Cells. Molecular Nutrition & Food Research. e2200090
Lamson NG, Fein KC, Gleeson JP, et al. (2022) The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207829119
Gleeson JP, Chaudhary N, Fein KC, et al. (2022) Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations. Science Advances. 8: eabm6865
Fein KC, Gleeson JP, Newby AN, et al. (2021) Intestinal permeation enhancers enable oral delivery of macromolecules up to 70 kDa in size. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
Melamed JR, Hajj KA, Chaudhary N, et al. (2021) Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society
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