Kevin J. Sampson, Ph.D.
Affiliations: | 2004 | Duke University, Durham, NC |
Area:
Biomedical Engineering, Neuroscience Biology, General Biophysics, Medical BiophysicsGoogle:
"Kevin Sampson"Parents
Sign in to add mentor| Craig S. Henriquez | grad student | 2004 | Duke | |
| (Quantification of action potential duration (APD) dispersion in intact myocardium and consequences for conduction block.) | ||||
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Publications
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| Zou X, Shanmugam SK, Kanner SA, et al. (2023) Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex. Elife. 12 |
| Zou X, Wu X, Sampson KJ, et al. (2022) Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels. Frontiers in Physiology. 13: 902224 |
| Redel-Traub G, Sampson KJ, Kass RS, et al. (2022) Potassium Channels as Therapeutic Targets in Pulmonary Arterial Hypertension. Biomolecules. 12 |
| Chen L, Peng G, Comollo TW, et al. (2022) Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements. Frontiers in Physiology. 13: 903050 |
| Comollo TW, Zou X, Zhang C, et al. (2022) Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers. Channels (Austin, Tex.). 16: 173-184 |
| Johnson M, Gomez-Galeno J, Ryan D, et al. (2021) Human iPSC-derived Cardiomyocytes and Pyridyl-Phenyl Mexiletine Analogs. Bioorganic & Medicinal Chemistry Letters. 128162 |
| Cashman JR, Ryan D, McKeithan WL, et al. (2021) Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes. Journal of Medicinal Chemistry |
| McKeithan WL, Feyen DAM, Bruyneel AAN, et al. (2020) Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity. Cell Stem Cell |
| Wu X, Perez ME, Sampson KJ, et al. (2019) Determining Functional KCNQ1/KCNE1 Subunit Interactions in the KCNQ1/KCNE1 Channel Biophysical Journal. 116: 539a |
| Bohnen MS, Roman-Campos D, Terrenoire C, et al. (2017) The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery. Journal of the American Heart Association. 6 |