Erik R. Feest, Ph.D.
Affiliations: | 2013 | Bioengineering | University of Washington, Seattle, Seattle, WA |
Area:
Biomedical Engineering, Physiology Biology, General Biophysics, BiochemistryGoogle:
"Erik Feest"Parents
Sign in to add mentorMichael Regnier | grad student | 2013 | University of Washington | |
(Engineering troponin C with altered Calcium ion (II) binding properties to study mechanisms of enhanced contraction of cardiac muscle from healthy and infarcted hearts.) |
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Publications
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Feest ER, Steven Korte F, Tu AY, et al. (2014) Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts. Journal of Molecular and Cellular Cardiology. 72: 219-27 |
Rao VS, Korte FS, Razumova MV, et al. (2013) N-terminal phosphorylation of cardiac troponin-I reduces length-dependent calcium sensitivity of contraction in cardiac muscle. The Journal of Physiology. 591: 475-90 |
Korte FS, Feest ER, Razumova MV, et al. (2012) Enhanced Ca2+ binding of cardiac troponin reduces sarcomere length dependence of contractile activation independently of strong crossbridges. American Journal of Physiology. Heart and Circulatory Physiology. 303: H863-70 |
Korte FS, Dai J, Buckley K, et al. (2011) Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. Journal of Molecular and Cellular Cardiology. 51: 894-901 |
Martyn DA, Korte S, Razumova M, et al. (2011) Both PKA Treatment and Cardiac Troponin-I N-Terminal Phosphorylation Alone Decrease Ca-Sensitivity and Eliminate Length-Dependent Activation in Skinned Cardiac Muscle Biophysical Journal. 100: 453a |
Korte FS, Feest ER, Razumova MV, et al. (2010) Sarcomere Length Dependent Contractile Activation is Reduced in Rat Trabeculae Exchanged with cTn Containing the L48Q cTnC Variant Independently of Strong Binding Cross-Bridges Biophysical Journal. 98: 356a |
Korte FS, Razumova MV, Feest ER, et al. (2010) PKA Phosphorylation Has No Effect on the Force-PCA Relationship or Length Dependent Activation Following L48Q cTNC-Tn Exchange in Rat Demembranated Trabeculae Biophysical Journal. 98: 6a |
Feest ER, Tu A, Luo C, et al. (2009) Effect of Varying Mutant Troponin C Content on Contractile Properties of Striated Muscle Biophysical Journal. 96: 228a |