Christopher C. Valley, Ph.D.
Affiliations: | 2012 | Biomedical Engineering | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Biomedical EngineeringGoogle:
"Christopher Valley"Parents
Sign in to add mentor| Jonathan N. Sachs | grad student | 2012 | UMN | |
| (Ligand binding and receptor network formation in the Tumor Necrosis Factor superfamily.) | ||||
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Publications
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| Strainic MG, Pohlmann E, Valley CC, et al. (2019) RTK signaling requires C3ar1/C5ar1 and IL-6R joint signaling to repress dominant PTEN, SOCS1/3 and PHLPP restraint. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
| Brandsma AM, Schwartz SL, Wester MJ, et al. (2018) Mechanisms of inside-out signaling of the high-affinity IgG receptor FcγRI. Science Signaling. 11 |
| Freed DM, Bessman NJ, Kiyatkin A, et al. (2017) EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell |
| Valley CC, Lewis AK, Sachs JN. (2017) Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors. Biochimica Et Biophysica Acta |
| Lewis AK, Valley CC, Peery SL, et al. (2016) Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function. Journal of Molecular Biology |
| Lewis AK, Dunleavy KM, Senkow TL, et al. (2016) Oxidation increases the strength of the methionine-aromatic interaction. Nature Chemical Biology |
| Valley CC, Arndt-Jovin DJ, Karedla N, et al. (2015) Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer. Molecular Biology of the Cell. 26: 4087-99 |
| Valley CC, Arndt-Jovin DJ, Jovin TM, et al. (2015) Inside-Out Signaling of Oncogenic EGFR Mutants Promotes Ligand-Independent Dimerization Biophysical Journal. 108: 351a |
| Valley CC, Lidke KA, Lidke DS. (2014) The spatiotemporal organization of ErbB receptors: insights from microscopy. Cold Spring Harbor Perspectives in Biology. 6 |
| Valley CC, Low-Nam ST, Steinkamp MP, et al. (2014) Single Molecule Imaging Reveals that Activating Kinase Domain Mutations Reduce EGFR Mobility and Enhance Dimerization Biophysical Journal. 106: 102a |