Jan-Hung Chen, Ph.D.
Affiliations: | 2011 | Mechanical and Industrial Engineering | University of Toronto, Toronto, ON, Canada |
Area:
Biomedical Engineering, Cell BiologyGoogle:
"Jan-Hung Chen"Parents
Sign in to add mentor| Craig A. Simmons | grad student | 2011 | University of Toronto | |
| (Roles for Matrix Mechanics in Regulating Aortic Valve Interstitial Cell Pathological Differentiation.) | ||||
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Publications
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| Wyss K, Yip CY, Mirzaei Z, et al. (2012) The elastic properties of valve interstitial cells undergoing pathological differentiation. Journal of Biomechanics. 45: 882-7 |
| Chen JH, Simmons CA. (2011) Cell-matrix interactions in the pathobiology of calcific aortic valve disease: critical roles for matricellular, matricrine, and matrix mechanics cues. Circulation Research. 108: 1510-24 |
| Chen JH, Chen WL, Sider KL, et al. (2011) β-catenin mediates mechanically regulated, transforming growth factor-β1-induced myofibroblast differentiation of aortic valve interstitial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 590-7 |
| Moraes C, Chen JH, Sun Y, et al. (2010) Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation. Lab On a Chip. 10: 227-34 |
| Chen JH, Liu C, You L, et al. (2010) Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone. Journal of Biomechanics. 43: 108-18 |
| Yip CY, Chen JH, Zhao R, et al. (2009) Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 936-42 |
| Chen JH, Yip CY, Sone ED, et al. (2009) Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential. The American Journal of Pathology. 174: 1109-19 |