Kelly A. Purpura, Ph.D.

Affiliations: 
2010 Chemical Engineering and Applied Chemistry University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Biomedical Engineering
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"Kelly Purpura"

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Peter W. Zandstra grad student 2010 University of Toronto
 (Controlling the Emergence of Hematopoietic Progenitor Cells from Pluripotent Stem Cells.)
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Publications

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Trainor N, Purpura KA, Middleton K, et al. (2023) Automated production of gene-modified chimeric antigen receptor T cells using the Cocoon Platform. Cytotherapy
Purpura KA, Bratt-Leal AM, Hammersmith KA, et al. (2012) Systematic engineering of 3D pluripotent stem cell niches to guide blood development. Biomaterials. 33: 1271-80
Tumarkin E, Tzadu L, Csaszar E, et al. (2011) High-throughput combinatorial cell co-culture using microfluidics. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 653-62
Rahman N, Purpura KA, Wylie RG, et al. (2010) The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells Biomaterials. 31: 8262-8270
Purpura KA, George SH, Dang SM, et al. (2008) Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner. Stem Cells (Dayton, Ohio). 26: 2832-42
Coles-Takabe BL, Brain I, Purpura KA, et al. (2008) Don't look: growing clonal versus nonclonal neural stem cell colonies. Stem Cells (Dayton, Ohio). 26: 2938-44
Purpura KA, Morin J, Zandstra PW. (2008) Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell-derived mesoderm and blood progenitors in a defined, serum-free media. Experimental Hematology. 36: 1186-98
Madlambayan GJ, Rogers I, Purpura KA, et al. (2006) Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 1020-30
Purpura KA, Aubin JE, Zandstra PW. (2004) Sustained in vitro expansion of bone progenitors is cell density dependent. Stem Cells (Dayton, Ohio). 22: 39-50
Purpura KA, Zandstra PW, Aubin JE. (2003) Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations. Journal of Cellular Biochemistry. 90: 109-20
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