Frédéric Bois

Affiliations: 
Compiègne 
Area:
Pharmacokinetics, Systems biology, Predictive toxicology, Mathematical modelling, Clustering,
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"Frédéric Bois"
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Publications

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Tebby C, van der Voet H, de Sousa G, et al. (2020) A generic PBTK model implemented in the MCRA platform: Predictive performance and uses in risk assessment of chemicals. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111440
Exner T, Farcal L, Bachler D, et al. (2019) OpenRiskNet Part I: Development of an open e-infrastructure predictive toxicology and risk assessment F1000research. 8
Codaccioni M, Bois F, Brochot C. (2019) Placental transfer of xenobiotics in pregnancy physiologically-based pharmacokinetic models: Structure and data Computational Toxicology. 12: 100111
Grech A, Tebby C, Brochot C, et al. (2018) Generic physiologically-based toxicokinetic modelling for fish: Integration of environmental factors and species variability. The Science of the Total Environment. 651: 516-531
Dorne J, Amzal B, Quignot N, et al. (2018) Reconnecting exposure, toxicokinetics and toxicity in food safety: OpenFoodTox and TKplate for human health, animal health and ecological risk assessment Toxicology Letters. 295: S29
Dorne J, Amzal B, Quignot N, et al. (2018) Developing TK databases and tools to support food safety assessment Toxicology Letters. 295: S5-S6
Leclerc E, Hamon J, Bois FY. (2016) Investigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver-kidney microfluidic data and pharmacokinetic-system biology models. Journal of Applied Toxicology : Jat. 36: 330-9
Leclerc E, Hamon J, Claude I, et al. (2015) Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion. Cell Biology and Toxicology. 31: 173-85
Bricks T, Hamon J, Fleury MJ, et al. (2015) Investigation of omeprazole and phenacetin first-pass metabolism in humans using a microscale bioreactor and pharmacokinetic models. Biopharmaceutics & Drug Disposition. 36: 275-93
Hamon J, Renner M, Jamei M, et al. (2015) Quantitative in vitro to in vivo extrapolation of tissues toxicity. Toxicology in Vitro : An International Journal Published in Association With Bibra. 30: 203-16
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