Nikolaos G. Sgourakis, Ph.D.
Affiliations: | 2009 | Rensselaer Polytechnic Institute, Troy, NY, United States |
Area:
General Biophysics, Molecular BiologyGoogle:
"Nikolaos Sgourakis"Parents
Sign in to add mentor| Angel E. Garcia | grad student | 2009 | RPI | |
| (Study of protein conformational and interaction dynamics by molecular dynamics simulations and nuclear magnetic resonance experiments.) | ||||
| David Baker | grad student | 2010-2012 | (Computational Biology Tree) | |
| Ad Bax | grad student | 2012-2015 | (Physics Tree) | |
Children
Sign in to add trainee| Scarlett A Dvorkin | post-doc | 2019-2020 | (Chemistry Tree) |
| Andrew C McShan | post-doc | 2020-2022 | Children’s Hospital of Philadelphia / University of Pennsylvania |
BETA: Related publications
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Publications
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| Du H, Mallik L, Hwang D, et al. (2024) Targeting peptide antigens using a multiallelic MHC I-binding system. Nature Biotechnology |
| McShan AC, Flores-Solis D, Sun Y, et al. (2023) Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition. Nature Communications. 14: 8204 |
| McShan AC, Devlin CA, Papadaki GF, et al. (2022) TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules. Nature Chemical Biology |
| McShan AC, Devlin CA, Morozov GI, et al. (2021) TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap. Nature Communications. 12: 3174 |
| Nerli S, De Paula VS, McShan AC, et al. (2021) Backbone-independent NMR resonance assignments of methyl probes in large proteins. Nature Communications. 12: 691 |
| O'Rourke SM, Morozov GI, Roberts JT, et al. (2020) Production of soluble pMHC-I molecules in mammalian cells using the molecular chaperone TAPBPR. Protein Engineering, Design & Selection : Peds |
| Leman JK, Weitzner BD, Lewis SM, et al. (2020) Macromolecular modeling and design in Rosetta: recent methods and frameworks. Nature Methods |
| Overall SA, Toor JS, Hao S, et al. (2020) High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange. Nature Communications. 11: 1909 |
| Wei KY, Moschidi D, Bick MJ, et al. (2020) Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proceedings of the National Academy of Sciences of the United States of America |
| De Paula VS, Jude KM, Nerli S, et al. (2020) Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch. Proceedings of the National Academy of Sciences of the United States of America |