Margarida D. Amaral
Affiliations: | Biochemistry | Faculdade de Ciências da Universidade de Lisboa |
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| Ferreira FC, Amaral MD, Bacalhau M, et al. (2024) PTI-801 (posenacaftor) shares a common mechanism with VX-445 (elexacaftor) to rescue p.Phe508del-CFTR. European Journal of Pharmacology. 967: 176390 |
| Railean V, Rodrigues CS, Ramalho SS, et al. (2023) Personalized medicine: Function of CFTR variant p.Arg334Trp is rescued by currently available CFTR modulators. Frontiers in Molecular Biosciences. 10: 1155705 |
| Santos L, Nascimento R, Duarte A, et al. (2023) Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells. Cell & Bioscience. 13: 26 |
| Bacalhau M, Ferreira FC, Silva IAL, et al. (2023) Additive Potentiation of R334W-CFTR Function by Novel Small Molecules. Journal of Personalized Medicine. 13 |
| Bacalhau M, Ferreira FC, Kmit A, et al. (2022) Identification of Novel F508del-CFTR traffic correctors among triazole derivatives. European Journal of Pharmacology. 175396 |
| Amaral MD, Harrison PT. (2022) Development of novel therapeutics for all individuals with CF (the future goes on). Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society |
| Rodenburg LW, Delpiano L, Railean V, et al. (2022) Drug Repurposing for Cystic Fibrosis: Identification of Drugs That Induce CFTR-Independent Fluid Secretion in Nasal Organoids. International Journal of Molecular Sciences. 23 |
| Amaral MD. (2022) Using the genome to correct the ion transport defect in cystic fibrosis. The Journal of Physiology |
| Ferreira JF, Silva IAL, Botelho HM, et al. (2022) Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids. Cells. 11 |
| Quaresma MC, Botelho HM, Pankonien I, et al. (2022) Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial-mesenchymal transition. Life Science Alliance. 5 |