Laoise McNamara

Affiliations: 
National University of Ireland Galway, Ireland 
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"Laoise McNamara"
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Bukhari MMM, Khabooshani M, Naqvi SM, et al. (2025) Estrogen deficiency alters vascularization and mineralization dynamics: insight from a novel 3-D humanized and vascularized bone organoid model. American Journal of Physiology. Cell Physiology. 328: C743-C756
Naqvi SM, O'Sullivan LM, Allison H, et al. (2024) Altered extracellular matrix and mechanotransduction gene expression in rat bone tissue following long-term estrogen deficiency. Jbmr Plus. 8: ziae098
Kumar V, Naqvi SM, Verbruggen A, et al. (2024) A mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteolytic effects of breast cancer cells. Cell Reports. 43: 114043
Verbruggen ASK, McNamara LM. (2023) Mechanoregulation may drive osteolysis during bone metastasis: A finite element analysis of the mechanical environment within bone tissue during bone metastasis and osteolytic resorption. Journal of the Mechanical Behavior of Biomedical Materials. 138: 105662
Verbruggen ASK, McCarthy EC, Dwyer RM, et al. (2022) Temporal and spatial changes in bone mineral content and mechanical properties during breast-cancer bone metastases. Bone Reports. 17: 101597
McNamara LM. (2021) Osteocytes and Estrogen Deficiency. Current Osteoporosis Reports. 19: 592-603
Curtis KJ, Mai C, Martin H, et al. (2021) The Effect of Marrow Secretome and Culture Environment on the Rate of Metastatic Breast Cancer Cell Migration in Two and Three Dimensions. Molecular Biology of the Cell. mbcE19120682
Curtis KJ, Schiavi J, Mc Garrigle MJ, et al. (2020) Mechanical stimuli and matrix properties modulate cancer spheroid growth in three-dimensional gelatin culture. Journal of the Royal Society, Interface. 17: 20200568
Naqvi SM, Panadero Pérez JA, Kumar V, et al. (2020) A Novel 3D Osteoblast and Osteocyte Model Revealing Changes in Mineralization and Pro-osteoclastogenic Paracrine Signaling During Estrogen Deficiency. Frontiers in Bioengineering and Biotechnology. 8: 601
Watson L, Chen XZ, Ryan AE, et al. (2020) Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study. Cells. 9
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