Phillip Tai, Ph.D.

Affiliations: 
2010 University of Washington, Seattle, Seattle, WA 
Area:
Skeletal muscle
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"Phillip Tai"

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Stephen D. Hauschka grad student 2010 University of Washington
 (Skeletal and cardiac muscle-specific gene regulation by transcriptional elements of muscle creatine kinase intron-1.)
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Publications

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Xie Q, Chen X, Ma H, et al. (2024) Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. Embo Molecular Medicine
Pan X, Yue Y, Boftsi M, et al. (2021) Rational engineering of a functional CpG-free ITR for AAV gene therapy. Gene Therapy
Muhuri M, Zhan W, Maeda Y, et al. (2021) Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction. Frontiers in Immunology. 12: 674242
Xiao Y, Muhuri M, Li S, et al. (2019) Circumventing cellular immunity by miR142-mediated regulation sufficiently supports rAAV-delivered OVA expression without activating humoral immunity. Jci Insight. 5
Tai PW, Smith CL, Angello JC, et al. (2012) Analysis of fiber-type differences in reporter gene expression of β-gal transgenic muscle. Methods in Molecular Biology (Clifton, N.J.). 798: 445-59
Himeda CL, Tai PW, Hauschka SD. (2012) Analysis of muscle gene transcription in cultured skeletal muscle cells. Methods in Molecular Biology (Clifton, N.J.). 798: 425-43
Tai PW, Fisher-Aylor KI, Himeda CL, et al. (2011) Differentiation and fiber type-specific activity of a muscle creatine kinase intronic enhancer. Skeletal Muscle. 1: 25
Salva MZ, Himeda CL, Tai PW, et al. (2007) Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 320-9
Salva MZ, Himeda CL, Tai P, et al. (2006) 561. Novel Tissue-Specific Regulatory Cassettes Direct High-Level Transgene Expression in Skeletal and Cardiac Muscle Molecular Therapy. 13: S216
Salva MZ, Himeda CL, Tai P, et al. (2005) 266. Development of rAAV-Based Skeletal and Cardiac Muscle Regulatory Cassettes for Gene Therapy of Duchenne Muscular Dystrophy Molecular Therapy. 11
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