Yu-Chih Tsai, Ph.D.

Affiliations: 
2005 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Cellular and Molecular Biology
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"Yu-Chih Tsai"

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Kenneth A. Johnson grad student 2005 UT Austin
 (Kinetics of DNA polymerase conformational changes during nucleotide binding and incorporation.)
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Publications

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Höijer I, Tsai YC, Clark TA, et al. (2018) Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing. Human Mutation
Nguyen TT, Suryamohan K, Kuriakose B, et al. (2018) Comprehensive analysis of single molecule sequencing-derived complete genome and whole transcriptome of Hyposidra talaca nuclear polyhedrosis virus. Scientific Reports. 8: 8924
Tsai YC, Conlan S, Deming C, et al. (2016) Resolving the Complexity of Human Skin Metagenomes Using Single-Molecule Sequencing. Mbio. 7
Pirone-Davies C, Hoffmann M, Roberts RJ, et al. (2015) Genome-wide methylation patterns in Salmonella enterica Subsp. enterica Serovars. Plos One. 10: e0123639
Doi Y, Hazen TH, Boitano M, et al. (2014) Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing. Antimicrobial Agents and Chemotherapy. 58: 5947-53
Vilfan ID, Tsai YC, Clark TA, et al. (2013) Analysis of RNA base modification and structural rearrangement by single-molecule real-time detection of reverse transcription. Journal of Nanobiotechnology. 11: 8
Zhang Z, Revyakin A, Tsai Y, et al. (2012) Single-Molecule Insights on the Human RNA Polymerase II Transcription Regulation: Assembly of the Pre-Initiation Complex, Re-Initiation Scaffold, and the Roles of Activators Biophysical Journal. 102: 228a-229a
Revyakin A, Zhang Z, Coleman R, et al. (2011) Assembly and Regulation of the Human RNA Polymerase II Preinitiation Complex: A Single-Molecule Approach to a Complex Biological System Biophysical Journal. 100: 10a
Tsai YC, Jin Z, Johnson KA. (2009) Site-specific labeling of T7 DNA polymerase with a conformationally sensitive fluorophore and its use in detecting single-nucleotide polymorphisms. Analytical Biochemistry. 384: 136-44
Tsai YC, Johnson KA. (2006) A new paradigm for DNA polymerase specificity. Biochemistry. 45: 9675-87
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