Shannon L. Stroschein, Ph.D.

Affiliations: 
2001 University of California, Berkeley, Berkeley, CA, United States 
Area:
Signal transduction pathways mediated by receptors and the mechanisms controlling the activity of the receptor kinases
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"Shannon Stroschein"

Parents

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Kunxin Luo grad student 2001 UC Berkeley
 (Regulation of transforming growth factor-beta signaling and the SnoN oncoprotein.)
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Publications

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Pan D, Estévez-Salmerón LD, Stroschein SL, et al. (2005) The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines. The Journal of Biological Chemistry. 280: 15992-6001
Stroschein SL, Bonni S, Wrana JL, et al. (2001) Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN. Genes & Development. 15: 2822-36
Bonni S, Wang HR, Causing CG, et al. (2001) TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation. Nature Cell Biology. 3: 587-95
Stroschein SL, Wang W, Zhou S, et al. (1999) Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science (New York, N.Y.). 286: 771-4
Luo K, Stroschein SL, Wang W, et al. (1999) The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes & Development. 13: 2196-206
Stroschein SL, Wang W, Luo K. (1999) Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation. The Journal of Biological Chemistry. 274: 9431-41
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