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James H. McKerrow

Affiliations: 
Biochemistry and Molecular Biology University of California, San Francisco, San Francisco, CA 
Area:
Biochemistry, Parasitology Biology
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"James McKerrow"
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Parents

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Children

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Jason P. Salter grad student 2001 UCSF
Rebecca B. Blank grad student 2005 UCSF
Marla E. Abodeely grad student 2006 UCSF
Kelly N. DuBois grad student 2007 UCSF
Theresa C. O'Brien grad student 2007 UCSF
Ryan K. Swenerton grad student 2009 UCSF
Jessica Ingram grad student 2011 UCSF
Mari Nishino grad student 2011 UCSF
Shuyi Zhang grad student 2011 UCSF
Kyriacos Koupparis grad student 2012 UCSF
Emmitt R. Jolly post-doc 2004-2008 UCSF School of Medicine (Chemistry Tree)

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Publications

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Wozniak JM, Silva TA, Thomas D, et al. (2020) Molecular dissection of chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. Plos Neglected Tropical Diseases. 14: e0007980
Singh B, Bernatchez JA, McCall LI, et al. (2020) Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors. Acs Medicinal Chemistry Letters. 11: 249-257
Chenna BC, Li L, Mellott D, et al. (2020) Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity. Journal of Medicinal Chemistry
Shing B, Singh S, Podust LM, et al. (2020) The antifungal drug isavuconazole is both amebicidal and cysticidal against . Antimicrobial Agents and Chemotherapy
Chenna BC, Li L, Mellott DM, et al. (2020) PeptidomimeticVinyl Heterocyclic Inhibitors of CruzainEffect Antitrypanosomal Activity Journal of Medicinal Chemistry
Shi D, Chahal KK, Oto P, et al. (2019) Identification of four amoebicidal non-toxic compounds by a molecular docking screen of Naegleria fowleri sterol Δ8-Δ7-isomerase and phenotypic assays. Acs Infectious Diseases
Rebello KM, McKerrow JH, Mota EM, et al. (2018) Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms. Plos Neglected Tropical Diseases. 12: e0006923
White Bear J, Long T, Skinner D, et al. (2018) Predictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data. Scientific Reports. 8: 13092
McKerrow JH. (2018) The diverse roles of cysteine proteases in parasites and their suitability as drug targets. Plos Neglected Tropical Diseases. 12: e0005639
McKerrow JH. (2018) Update on drug development targeting parasite cysteine proteases. Plos Neglected Tropical Diseases. 12: e0005850
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