David T. Lodowski, Ph.D.

Affiliations: 
2004 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Biochemistry
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"David Lodowski"

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John J. Tesmer grad student 2004 UT Austin
 (Structural basis for the regulation of GRK2 by Gbetagamma.)
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Publications

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Du Y, Duc NM, Rasmussen SGF, et al. (2019) Assembly of a GPCR-G Protein Complex. Cell
Blankenship E, Vahedi-Faridi A, Lodowski DT. (2015) The High-Resolution Structure of Activated Opsin Reveals a Conserved Solvent Network in the Transmembrane Region Essential for Activation. Structure (London, England : 1993). 23: 2358-64
Ernst OP, Lodowski DT, Elstner M, et al. (2014) Microbial and animal rhodopsins: structures, functions, and molecular mechanisms. Chemical Reviews. 114: 126-63
Salon JA, Lodowski DT, Palczewski K. (2011) The significance of G protein-coupled receptor crystallography for drug discovery. Pharmacological Reviews. 63: 901-37
Jastrzebska B, Ringler P, Lodowski DT, et al. (2011) Rhodopsin-transducin heteropentamer: three-dimensional structure and biochemical characterization. Journal of Structural Biology. 176: 387-94
Lodowski DT, Palczewski K, Miyagi M. (2010) Conformational changes in the g protein-coupled receptor rhodopsin revealed by histidine hydrogen-deuterium exchange. Biochemistry. 49: 9425-7
Goc A, Chami M, Lodowski DT, et al. (2010) Structural characterization of the rod cGMP phosphodiesterase 6. Journal of Molecular Biology. 401: 363-73
Becka S, Zhang P, Craig SE, et al. (2010) Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases. Cell Communication & Adhesion. 17: 34-47
Tesmer JJ, Tesmer VM, Lodowski DT, et al. (2010) Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. Journal of Medicinal Chemistry. 53: 1867-70
Lodowski DT, Palczewski K. (2009) Chemokine receptors and other G protein-coupled receptors. Current Opinion in Hiv and Aids. 4: 88-95
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