Angelia D. Lockett, Ph.D.

Affiliations: 
2008 Cellular and Integrative Physiology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Cell Biology, Physiology Biology
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"Angelia Lockett"

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Maureen Harrington grad student 2008 Indiana University Bloomington
 (Coordination of LPS, TNFalpha and IL-1beta signaling by IRAK-1 posttranslational modification.)
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Publications

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Lockett AD, Wu Y, Gunst SJ. (2017) Elastase Alters Contractility and Promotes an Inflammatory Synthetic Phenotype in Airway Smooth Muscle Tissues. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00334.2017
Lockett AD. (2017) Alpha-1 Antitrypsin Transcytosis and Secretion. Methods in Molecular Biology (Clifton, N.J.). 1639: 173-184
Serban KA, Petrusca DN, Mikosz A, et al. (2017) Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure. Plos One. 12: e0176073
Lockett AD, Petrusca DN, Justice MJ, et al. (2015) Scavenger Receptor Class B, Type I mediated uptake of A1AT by Pulmonary Endothelial Cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00376.2014
Toney BM, Fisher AJ, Albrecht M, et al. (2014) Selective endothelin-A receptor blockade attenuates endotoxin-induced pulmonary hypertension and pulmonary vascular dysfunction. Pulmonary Circulation. 4: 300-10
Lockett AD, Brown MB, Santos-Falcon N, et al. (2014) Active trafficking of alpha 1 antitrypsin across the lung endothelium. Plos One. 9: e93979
Lockett AD, Kimani S, Ddungu G, et al. (2013) α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α. American Journal of Respiratory Cell and Molecular Biology. 49: 143-50
Lockett AD, Van Demark M, Gu Y, et al. (2012) Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases. Molecular Medicine (Cambridge, Mass.). 18: 445-54
Sohrab S, Petrusca DN, Lockett AD, et al. (2009) Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3149-58
Lockett A, Goebl MG, Harrington MA. (2008) Transient membrane recruitment of IRAK-1 in response to LPS and IL-1beta requires TNF R1. American Journal of Physiology. Cell Physiology. 295: C313-23
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