Domenico L. Gatti

Affiliations: 
Biochemistry and Molecular Biology Wayne State University, Detroit, MI, United States 
Area:
Biochemistry, Molecular Biology
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"Domenico Gatti"

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Fathima R. Kona grad student 2008 Wayne State
Parthasarathi Dastidar post-doc 1996-1998 Wayne State (Chemistry Tree)
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Publications

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Acin-Perez R, Gatti DL, Bai Y, et al. (2011) Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: coupled mechanisms of energy metabolism regulation. Cell Metabolism. 13: 712-9
Ackerman SH, Gatti DL. (2011) The contribution of coevolving residues to the stability of KDO8P synthase. Plos One. 6: e17459
Tao P, Schlegel HB, Gatti DL. (2010) Common basis for the mechanism of metallo and non-metallo KDO8P synthases Journal of Inorganic Biochemistry. 104: 1267-1275
Meulemans A, Seneca S, Pribyl T, et al. (2010) Defining the pathogenesis of the human Atp12p W94R mutation using a Saccharomyces cerevisiae yeast model. The Journal of Biological Chemistry. 285: 4099-109
Tao P, Gatti DL, Schlegel HB. (2009) The energy landscape of 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochemistry. 48: 11706-14
Kona F, Tao P, Martin P, et al. (2009) Electronic structure of the metal center in the Cd(2+), Zn(2+), and Cu(2+) substituted forms of KDO8P synthase: implications for catalysis. Biochemistry. 48: 3610-30
Kona F, Xu X, Martin P, et al. (2007) Structural and mechanistic changes along an engineered path from metallo to nonmetallo 3-deoxy-D-manno-octulosonate 8-phosphate synthases. Biochemistry. 46: 4532-44
Xu X, Kona F, Wang J, et al. (2005) The catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase: role of the L7 loop. Biochemistry. 44: 12434-44
Cole LJ, Gatti DL, Entsch B, et al. (2005) Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase Biochemistry. 44: 8047-8058
Hinton A, Gatti DL, Ackerman SH. (2004) The molecular chaperone, Atp12p, from Homo sapiens. In vitro studies with purified wild type and mutant (E240K) proteins. The Journal of Biological Chemistry. 279: 9016-22
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