Timothy J. Parnell, Ph.D.

Affiliations: 
2000 University of Iowa, Iowa City, IA 
Area:
Genetics, Molecular Biology
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"Timothy Parnell"

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Pamela K. Geyer grad student 2000 University of Iowa
 (Insights into the mechanism of gypsy insulator function: Are higher order chromatin structures required?)
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Publications

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Shukla PK, Bissell JE, Kumar S, et al. (2023) Structure and functional determinants of Rad6-Bre1 subunits in the histone H2B ubiquitin-conjugating complex. Nucleic Acids Research
Parnell EJ, Parnell TJ, Stillman DJ. (2022) Genetic analysis argues for a coactivator function for the Saccharomyces cerevisiae Tup1 corepressor. Genetics. 219
Connell Z, Parnell TJ, McCullough LL, et al. (2021) The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II. Nucleic Acids Research
Parnell EJ, Parnell TJ, Yan C, et al. (2020) Ash1 and Tup1 dependent repression of the Saccharomyces cerevisiae HO promoter requires activator-dependent nucleosome eviction. Plos Genetics. 16: e1009133
Schlichter A, Kasten MM, Parnell TJ, et al. (2020) Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes. Elife. 9
Sdano MA, Fulcher JM, Palani S, et al. (2017) A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. Elife. 6
Ramakrishnan S, Pokhrel S, Palani S, et al. (2016) Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription. Nature Communications. 7: 11949
Huang F, Ramakrishnan S, Pokhrel S, et al. (2015) Interaction of the Jhd2 H3K4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination. The Journal of Biological Chemistry
Parnell TJ, Schlichter A, Wilson BG, et al. (2015) The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism. Elife. 4: e06073
Potok ME, Nix DA, Parnell TJ, et al. (2013) Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern. Cell. 153: 759-72
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