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Christine M. Lovly, Ph.D.

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Cell Biology
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"Christine Lovly"

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Helen Piwnica-Worms grad student 2006 Washington University
 (DNA damage induced phosphorylation, activation, and ubiquitin-mediated proteolysis of the Chk2 tumor suppressor protein.)
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Publications

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Sivapalan L, Iams WT, Belcaid Z, et al. (2023) Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. OF1-OF14
Desai A, Lovly CM. (2023) Strategies to overcome resistance to ALK inhibitors in non-small cell lung cancer: a narrative review. Translational Lung Cancer Research. 12: 615-628
Ettinger DS, Wood DE, Aisner DL, et al. (2023) NCCN GuidelinesĀ® Insights: Non-Small Cell Lung Cancer, Version 2.2023. Journal of the National Comprehensive Cancer Network : Jnccn. 21: 340-350
Lin HM, Wu Y, Yin Y, et al. (2022) Real-world ALK Testing Trends in Patients With Advanced Non-Small-Cell Lung Cancer in the United States. Clinical Lung Cancer
Remsing Rix LL, Sumi NJ, Hu Q, et al. (2022) IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells. Science Signaling. 15: eabj5879
Sato H, Kubota D, Qiao H, et al. (2022) SRC Family Kinase Inhibition Targets YES1 and YAP1 as Primary Drivers of Lung Cancer and as Mediators of Acquired Resistance to ALK and Epidermal Growth Factor Receptor Inhibitors. Jco Precision Oncology. 6: e2200088
Brown BP, Zhang YK, Kim S, et al. (2022) Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206588119
Ettinger DS, Wood DE, Aisner DL, et al. (2022) Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : Jnccn. 20: 497-530
Ettinger DS, Wood DE, Aisner DL, et al. (2021) NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 2.2021. Journal of the National Comprehensive Cancer Network : Jnccn. 19: 254-266
Du Z, Brown BP, Kim S, et al. (2021) Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting. Nature Communications. 12: 1382
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