Judith A. Cam, Ph.D.

Affiliations: 
2004 Washington University, Saint Louis, St. Louis, MO 
Area:
Neuroscience Biology
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"Judith Cam"

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Guojun Bu grad student 2004 Washington University
 (Opposing roles of the LDL receptor -related protein (LRP1) and the LDL receptor -related protein 1B (LRP1B) in beta-amyloid precursor protein (APP) trafficking and processing.)
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Publications

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Snow AD, Castillo GM, Nguyen BP, et al. (2019) The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles. Scientific Reports. 9: 561
Fuentealba RA, Barría MI, Lee J, et al. (2007) ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity. Molecular Neurodegeneration. 2: 14
Bu G, Cam J, Zerbinatti C. (2006) LRP in amyloid-beta production and metabolism. Annals of the New York Academy of Sciences. 1086: 35-53
Zerbinatti CV, Wahrle SE, Kim H, et al. (2006) Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice. The Journal of Biological Chemistry. 281: 36180-6
Cam JA, Bu G. (2006) Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family. Molecular Neurodegeneration. 1: 8
Cam JA, Zerbinatti CV, Li Y, et al. (2005) Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein. The Journal of Biological Chemistry. 280: 15464-70
Cam JA, Zerbinatti CV, Knisely JM, et al. (2004) The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production. The Journal of Biological Chemistry. 279: 29639-46
Zerbinatti CV, Wozniak DF, Cirrito J, et al. (2004) Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein. Proceedings of the National Academy of Sciences of the United States of America. 101: 1075-80
Li Y, Cam J, Bu G. (2001) Low-density lipoprotein receptor family: Endocytosis and signal transduction Molecular Neurobiology. 23: 53-67
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