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William F. Bosron

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry
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"William Bosron"
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Parents

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Richard L. Prairie grad student University of Cincinnati
Bert Lester Vallee grad student (Chemistry Tree)

Children

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Thomas D. Hurley grad student 1990 Indiana University School of Medicine
Zejin Sun grad student 2004 Indiana University
Marissa A. Schiel grad student 2009 Indiana University

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Publications

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Edenberg HJ, Bosron WF. (2014) Alcohol Dehydrogenases Reference Module in Biomedical Research
Sanghani SP, Sanghani PC, Schiel MA, et al. (2009) Human carboxylesterases: an update on CES1, CES2 and CES3. Protein and Peptide Letters. 16: 1207-14
Janecki DJ, Bemis KG, Tegeler TJ, et al. (2007) A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme. Analytical Biochemistry. 369: 18-26
Schiel MA, Green SL, Davis WI, et al. (2007) Expression and characterization of a human carboxylesterase 2 splice variant. The Journal of Pharmacology and Experimental Therapeutics. 323: 94-101
Quinney SK, Sanghani SP, Davis WI, et al. (2005) Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide. The Journal of Pharmacology and Experimental Therapeutics. 313: 1011-6
Sanghani SP, Quinney SK, Fredenburg TB, et al. (2004) Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 505-11
Sun Z, Murry DJ, Sanghani SP, et al. (2004) Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1. The Journal of Pharmacology and Experimental Therapeutics. 310: 469-76
Sanghani SP, Quinney SK, Fredenburg TB, et al. (2003) Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4983-91
Sanghani PC, Robinson H, Bennett-Lovsey R, et al. (2003) Structure-function relationships in human Class III alcohol dehydrogenase (formaldehyde dehydrogenase). Chemico-Biological Interactions. 143: 195-200
Sanghani PC, Bosron WF, Hurley TD. (2002) Human glutathione-dependent formaldehyde dehydrogenase. Structural changes associated with ternary complex formation. Biochemistry. 41: 15189-94
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