Jiandong Chen
Affiliations: | Biology (Cell Biology, Microbiology, Molecular Biology) | University of South Florida, Tampa, FL, United States |
Area:
Molecular Biology, Cell Biology, Oncology, GeneticsGoogle:
"Jiandong Chen"Children
Sign in to add trainee| Daniele M Gilkes | grad student | University of South Florida | |
| Yu Pan | grad student | 2005 | University of South Florida |
| Cynthia LeBron | grad student | 2007 | University of South Florida |
| Daniele M. Gilkes | grad student | 2008 | University of South Florida |
| Neha Kabra | grad student | 2010 | University of South Florida |
| Brittany L. Cross | grad student | 2011 | University of South Florida |
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Publications
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| Karim RM, Yang L, Chen L, et al. (2022) Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromodomain. Journal of Medicinal Chemistry |
| Lu J, Chen L, Song Z, et al. (2021) Hypothermia effectively treats tumors with temperature-sensitive p53 mutations. Cancer Research |
| Li Q, Karim RM, Cheng M, et al. (2020) Inhibition of p53 DNA binding by a small molecule protects mice from radiation toxicity. Oncogene |
| Huang Q, Chen L, Schonbrunn E, et al. (2020) MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling. The Embo Journal. e104410 |
| Sang P, Shi Y, Lu J, et al. (2020) α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions. Journal of Medicinal Chemistry |
| He F, Borcherds W, Song T, et al. (2019) Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding. Proceedings of the National Academy of Sciences of the United States of America |
| Yang L, Song T, Cheng Q, et al. (2018) Mutant p53 sequestration of MDM2 acidic domain inhibits E3 ligase activity. Molecular and Cellular Biology |
| Huang Q, Chen L, Yang L, et al. (2018) MDMX acidic domain inhibits p53 DNA binding in vivo and regulates tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America |
| Yang L, Fang J, Chen J. (2017) Tumor cell senescence response produces aggressive variants. Cell Death Discovery. 3: 17049 |
| Borcherds W, Becker A, Chen L, et al. (2017) Optimal Affinity Enhancement by a Conserved Flexible Linker Controls p53 Mimicry in MdmX. Biophysical Journal |