Ronald C. Wek

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology
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"Ronald Wek"
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Misra J, Carlson KR, Spandau DF, et al. (2024) Multiple mechanisms activate GCN2 eIF2 kinase in response to diverse stress conditions. Nucleic Acids Research
Holmes MJ, Bastos MS, Dey V, et al. (2023) mRNA cap-binding protein eIF4E1 is a novel regulator of latency. Biorxiv : the Preprint Server For Biology
Levy JL, Mirek ET, Rodriguez EM, et al. (2023) GCN2 is required to maintain core body temperature in mice during acute cold. American Journal of Physiology. Endocrinology and Metabolism
Wek RC, Anthony TG, Staschke KA. (2023) Surviving and adapting to stress: Translational control and the integrated stress response. Antioxidants & Redox Signaling
Carlson KR, Georgiadis MM, Tameire F, et al. (2023) Activation of Gcn2 by small molecules designed to be inhibitors. The Journal of Biological Chemistry. 299: 104595
Amin PH, Carlson KR, Wek RC. (2022) An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response. The Journal of Biological Chemistry. 102864
Srivastava S, Jiang J, Misra J, et al. (2022) Asparagine bioavailability regulates the translation of MYC oncogene. Oncogene
Cordova RA, Misra J, Amin PH, et al. (2022) GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis. Elife. 11
Holmes MJ, Misra J, Wek RC. (2022) Analysis of Translational Control in the Integrated Stress Response by Polysome Profiling. Methods in Molecular Biology (Clifton, N.J.). 2428: 157-171
Jin D, Wek SA, Kudlapur NT, et al. (2021) Disease-associated mutations in a bifunctional aminoacyl-tRNA synthetase gene elicit the integrated stress response. The Journal of Biological Chemistry. 101203
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