Daniele Canzio, Ph.D.
Affiliations: | 2012 | Chemistry and Chemical Biology | University of California, San Francisco, San Francisco, CA |
Area:
Biochemistry, General Biophysics, GeneticsGoogle:
"Daniele Canzio"Parents
Sign in to add mentor| Geeta J. Narlikar | grad student | 2012 | UCSF | |
| (Histone mimicry in HPl is required for a conformational switch that regulates assembly of a minimal heterochromatin unit necessary for silencing in vivo.) | ||||
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Publications
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| Canzio D, Maniatis T. (2019) The generation of a protocadherin cell-surface recognition code for neural circuit assembly. Current Opinion in Neurobiology. 59: 213-220 |
| Vega-Benedetti AF, Loi E, Moi L, et al. (2019) Clustered protocadherins methylation alterations in cancer. Clinical Epigenetics. 11: 100 |
| Canzio D, Nwakeze CL, Horta A, et al. (2019) Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice. Cell |
| Mountoufaris G, Canzio D, Nwakeze CL, et al. (2018) Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly. Annual Review of Cell and Developmental Biology. 34: 471-493 |
| Guo Y, Xu Q, Canzio D, et al. (2015) CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 162: 900-10 |
| Canzio D, Larson A, Narlikar GJ. (2014) Mechanisms of functional promiscuity by HP1 proteins. Trends in Cell Biology. 24: 377-86 |
| Canzio D, Liao M, Naber N, et al. (2013) A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Nature. 496: 377-81 |
| Canzio D, Liang M, Naber N, et al. (2013) Abstract IA23: Functional and structural studies of HP1 heterochromatin Cancer Research. 73 |
| Armache KJ, Garlick JD, Canzio D, et al. (2011) Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution. Science (New York, N.Y.). 334: 977-82 |
| Canzio D, Chang EY, Shankar S, et al. (2011) Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly. Molecular Cell. 41: 67-81 |