Isam M. Qahwash, Ph.D.
Affiliations: | 2008 | University of Chicago, Chicago, IL |
Area:
Pathology, Molecular BiologyGoogle:
"Isam Qahwash"Parents
Sign in to add mentor| Stephen Charles Meredith | grad student | 2008 | Chicago | |
| (Effects of lipidation and characteristics of amyloid fibrils.) | ||||
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Publications
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| Bockhorn JJ, Lazar KL, Gasser AJ, et al. (2010) Novel semisynthetic method for generating full length beta-amyloid peptides. Biopolymers. 94: 511-20 |
| Paravastu AK, Qahwash I, Leapman RD, et al. (2009) Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proceedings of the National Academy of Sciences of the United States of America. 106: 7443-8 |
| Qahwash IM, Boire A, Lanning J, et al. (2007) Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity. The Journal of Biological Chemistry. 282: 36987-97 |
| He W, Lu Y, Qahwash I, et al. (2004) Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation. Nature Medicine. 10: 959-65 |
| Qahwash I, He W, Tomasselli A, et al. (2004) Processing amyloid precursor protein at the beta-site requires proper orientation to be accessed by BACE1. The Journal of Biological Chemistry. 279: 39010-6 |
| Qahwash I, Weiland KL, Lu Y, et al. (2003) Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates. The Journal of Biological Chemistry. 278: 23187-95 |
| Tomasselli AG, Qahwash I, Emmons TL, et al. (2003) Employing a superior BACE1 cleavage sequence to probe cellular APP processing. Journal of Neurochemistry. 84: 1006-17 |