Sarah E. Mortimer, Ph.D.
Affiliations: | 2005 | Brandeis University, Waltham, MA, United States |
Area:
Molecular BiologyGoogle:
"Sarah Mortimer"Parents
Sign in to add mentorLizbeth Hedstrom | grad student | 2005 | Brandeis | |
(Non-enzymatic functions of human inosine 5'-monophosphate dehydrogenase: Disruption of nucleic acid binding by retinal disease mutations and a connection to translation.) |
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Publications
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Mortimer SE, Xu D, McGrew D, et al. (2008) IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNA. The Journal of Biological Chemistry. 283: 36354-60 |
Bowne SJ, Sullivan LS, Mortimer SE, et al. (2006) Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosis. Investigative Ophthalmology & Visual Science. 47: 34-42 |
Mortimer SE, Hedstrom L. (2005) Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid binding. The Biochemical Journal. 390: 41-7 |
McLean JE, Hamaguchi N, Belenky P, et al. (2004) Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo. The Biochemical Journal. 379: 243-51 |