David S. Harburger, Ph.D.

Affiliations: 
2010 Yale University, New Haven, CT 
Area:
Molecular Biology, Cell Biology, Biochemistry
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"David Harburger"

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David A. Calderwood grad student 2010 Yale
 (Structure/function analysis of the kindlin family proteins.)
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Publications

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Simpson MA, Bradley WD, Harburger D, et al. (2015) Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase. The Journal of Biological Chemistry. 290: 8360-72
Brahme NN, Harburger DS, Kemp-O'Brien K, et al. (2013) Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics. The Journal of Biological Chemistry. 288: 35604-16
Bouaouina M, Harburger DS, Calderwood DA. (2012) Talin and signaling through integrins. Methods in Molecular Biology (Clifton, N.J.). 757: 325-47
Goult BT, Bouaouina M, Harburger DS, et al. (2009) The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation. Journal of Molecular Biology. 394: 944-56
Harburger DS, Bouaouina M, Calderwood DA. (2009) Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects. The Journal of Biological Chemistry. 284: 11485-97
Harburger DS, Calderwood DA. (2009) Integrin signalling at a glance. Journal of Cell Science. 122: 159-63
Lad Y, Jiang P, Ruskamo S, et al. (2008) Structural basis of the migfilin-filamin interaction and competition with integrin β tails Journal of Biological Chemistry. 283: 35154-35163
Lad Y, Harburger DS, Calderwood DA. (2007) Integrin cytoskeletal interactions. Methods in Enzymology. 426: 69-84
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