Ziba Razinia, Ph.D.

Affiliations: 
2012 Cell Biology Yale University, New Haven, CT 
Area:
Cell Biology, Molecular Biology, Biochemistry
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"Ziba Razinia"

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David A. Calderwood grad student 2012 Yale
 (Filamins in Cell Migration and Molecular Mechanism of their Regulation by the ASB2alpha-E3 Ubiquitin Ligase Complex.)
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Publications

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Razinia Z, Castagnino P, Xu T, et al. (2017) Stiffness-dependent motility and proliferation uncoupled by deletion of CD44. Scientific Reports. 7: 16499
Bae YH, Mui KL, Hsu BY, et al. (2014) A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling. Science Signaling. 7: ra57
Razinia Z, Baldassarre M, Cantelli G, et al. (2013) ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. The Journal of Biological Chemistry. 288: 32093-105
Baldassarre M, Razinia Z, Brahme NN, et al. (2012) Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells. Journal of Cell Science. 125: 3858-69
Razinia Z, Mäkelä T, Ylänne J, et al. (2012) Filamins in mechanosensing and signaling. Annual Review of Biophysics. 41: 227-46
Razinia Z, Baldassarre M, Bouaouina M, et al. (2011) The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain. Journal of Cell Science. 124: 2631-41
Lamsoul I, Burande CF, Razinia Z, et al. (2011) Functional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cells. The Journal of Biological Chemistry. 286: 30571-81
Chiswell BP, Stiegler AL, Razinia Z, et al. (2010) Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. Journal of Structural Biology. 170: 157-63
Ghazarian H, Coyle-Thompson C, Dalrymple W, et al. (2010) Exogenous hyalin and sea urchin gastrulation. Part IV: a direct adhesion assay - progress in identifying hyalin's active sites. Zygote (Cambridge, England). 18: 17-26
Baldassarre M, Razinia Z, Burande CF, et al. (2009) Filamins regulate cell spreading and initiation of cell migration. Plos One. 4: e7830
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