Srividya Swaminathan, Ph.D.
Affiliations: | 2013 | Genetic, Molecular, and Cell Biology | University of Southern California, Los Angeles, CA, United States |
Area:
Immunology, Molecular Biology, Cell BiologyGoogle:
"Srividya Swaminathan"Parents
Sign in to add mentor| Markus Muschen | grad student | 2013 | USC | |
| (Loss of checkpoint controls in acute lymphoblastic leukemia.) | ||||
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Publications
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| Li Y, Xue M, Deng X, et al. (2023) TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal. Cell Stem Cell. 30: 1072-1090.e10 |
| Kumar A, Taghi Khani A, Duault C, et al. (2023) Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia. Journal For Immunotherapy of Cancer. 11 |
| Taghi Khani A, Kumar A, Sanchez Ortiz A, et al. (2023) Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Communications Biology. 6: 295 |
| Cluff E, Magdaleno CC, Fernandez E, et al. (2022) Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells. Cancer Immunology, Immunotherapy : Cii |
| Kumar A, Lee SJ, Liu Q, et al. (2021) Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications. Star Protocols. 2: 100874 |
| Duault C, Kumar A, Taghi Khani A, et al. (2021) Activated Natural Killer Cells Predict Poor Clinical Prognosis in High-risk B- and T- cell Acute Lymphoblastic Leukemia. Blood |
| Swaminathan S, Hansen AS, Heftdal LD, et al. (2020) MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies. Nature Communications. 11: 2860 |
| Hurtz C, Carroll MP, Tasian SK, et al. (2020) DYRK1A Is Required to Alleviate Replication Stress in KMT2A-Rearranged Acute Lymphoblastic Leukemia Blood. 136: 39-40 |
| Duault C, Kumar A, Taghi Khani A, et al. (2020) Activated Natural Killer Cells Are Associated with Poor Clinical Prognosis in High-Risk B- and T- Cell Acute Lymphoblastic Leukemia Blood. 136: 39-39 |
| Swaminathan S, Heftdal LD, Liefwalker D, et al. (2019) MYC Oncogene Abrogates Natural Killer (NK) Cell-Mediated Immune Surveillance of B- and T- Lymphoid Malignancies By Suppressing STAT1/2-Type I IFN Signaling Blood. 134: 730-730 |