Lori N. Griner, Ph.D.

Affiliations: 
2013 Biology (Cell Biology, Microbiology, Molecular Biology) University of South Florida, Tampa, FL, United States 
Area:
Molecular Biology
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"Lori Griner"

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Gary W. Reuther grad student 2013 University of South Florida
 (The Mevalonate Pathway: A Potential Therapeutic Target for JAK2-driven Myeloproliferative Neoplasms.)
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Publications

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Basiorka AA, McGraw KL, De Ceuninck L, et al. (2016) Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41. Cancer Research
Mazzacurati L, Lambert QT, Pradhan A, et al. (2015) The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells. Oncotarget
Griner LN, McGraw KL, Johnson JO, et al. (2013) JAK2-V617F-mediated signalling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth. British Journal of Haematology. 160: 177-87
Basiorka AA, McGraw KL, Griner LN, et al. (2012) Lenalidomide Upregulates Erythropoietin Receptor Expression Through Inhibition of the E3-Ubiquitin Ligase Ring Finger Protein 41 (RNF41) Blood. 120: 3455-3455
Griner LN, McGraw KL, Johnson JO, et al. (2011) A Mechanistic Rationale for the Use of Statins to Enhance JAK Inhibitor Therapy in MPNs Blood. 118: 2816-2816
Griner LN, Reuther GW. (2010) Aggressive myeloid leukemia formation is directed by the Musashi 2/Numb pathway. Cancer Biology & Therapy. 10: 979-82
Pradhan A, Lambert QT, Griner LN, et al. (2010) Activation of JAK2-V617F by components of heterodimeric cytokine receptors. The Journal of Biological Chemistry. 285: 16651-63
Griner LN, McGraw KL, Johnson JO, et al. (2010) Requirement of Lipid Raft Integrity for Signaling by JAK2-V617F Blood. 116: 4191-4191
Pradhan AR, Lambert QT, Griner LN, et al. (2009) Activation of JAK2-V617F by Heterodimeric Receptor Components. Blood. 114: 2955-2955
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