Relja Popovic, Ph.D.

Affiliations: 
2008 Loyola University Chicago, Chicago, IL, United States 
Area:
Molecular Biology
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"Relja Popovic"

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Nancy J. Zeleznik-Le grad student 2008 Loyola University Chicago
 (Regulation of mir -196b by MLL and its overexpression by MLL fusions contributes to MLL leukemia.)
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Publications

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Cojocari D, Jin S, Purkal JJ, et al. (2018) 5-Azacytidine Induces NOXA and PUMA Expression to Prime AML Cells for Venetoclax-Mediated Apoptosis Blood. 132: 2644-2644
Ezponda T, Dupéré-Richer D, Will CM, et al. (2017) UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition. Cell Reports. 21: 628-640
Bellin RJ, Hilgenberg V, Popovic R, et al. (2017) Abstract 3812:JAK2andPTPN11mutations as potential biomarkers for BCL-xL inhibition as monotherapy and in combination therapy for acute myeloid leukemia Cancer Research. 77: 3812-3812
Shah MY, Martinez-Garcia E, Phillip JM, et al. (2016) MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents. Oncogene
Nabet B, Ó Broin P, Reyes JM, et al. (2015) Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape. Cell Reports. 12: 1300-13
Kumar K, Raza SS, Knab LM, et al. (2015) GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1. Scientific Reports. 5: 9489
Zhou Z, Gao J, Popovic R, et al. (2015) Strong expression of EZH2 and accumulation of trimethylated H3K27 in diffuse large B-cell lymphoma independent of cell of origin and EZH2 codon 641 mutation. Leukemia & Lymphoma. 1-7
Oyer J, Will C, Huang X, et al. (2015) Allele-Specific Crispr Targeting Reveals Epigenetic and Phenotypic Effects of a MMSET Gain of Function Mutation Found in Relapsed Acute Lymphoblastic Leukemia Blood. 126: 437-437
Ezponda T, Popovic R, Zheng Y, et al. (2015) Abstract B32: Loss of the histone demethylase UTX alters the gene expression prolife and contributes to the malignant phenotype of multiple myeloma cells. Clinical Cancer Research. 21
Nabet B, Broin PO, Reyes J, et al. (2015) Abstract 2209: Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape Cancer Research. 75: 2209-2209
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