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Brian M. Shewchuk

Affiliations: 
Biochemistry and Molecular Biology East Carolina University, Greenville, NC, United States 
Area:
Biochemistry, Molecular Biology
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"Brian Shewchuk"
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Parents

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Ross C. Hardison grad student 1997 Penn State

Children

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Tamra L. Hunsaker grad student 2012 East Carolina University
Alena O. Nakonechnaya grad student 2012 East Carolina University

Collaborators

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Publications

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Wang L, DeMarco SS, Peaks MS, et al. (2017) RARα/RXR Synergism Potentiates Retinoid Responsiveness in Cutaneous T Cell Lymphoma Cell Lines. Experimental Dermatology
Holt AW, Martin DN, Shaver PR, et al. (2016) Soluble guanylyl cyclase-activated cyclic GMP-dependent protein kinase inhibits arterial smooth muscle cell migration independent of VASP-serine 239 phosphorylation. Cellular Signalling
Nakonechnaya AO, Shewchuk BM. (2015) Growth hormone enhances LNCaP prostate cancer cell motility. Endocrine Research. 40: 97-105
Ho Y, Shewchuk BM, Liebhaber SA, et al. (2013) Distinct chromatin configurations regulate the initiation and the maintenance of hGH gene expression. Molecular and Cellular Biology. 33: 1723-34
Nakonechnaya AO, Jefferson HS, Chen X, et al. (2013) Differential effects of exogenous and autocrine growth hormone on LNCaP prostate cancer cell proliferation and survival. Journal of Cellular Biochemistry. 114: 1322-35
Hunsaker TL, Jefferson HS, Morrison JK, et al. (2012) POU1F1-mediated activation of hGH-N by deoxyribonuclease I hypersensitive site II of the human growth hormone locus control region. Journal of Molecular Biology. 415: 29-45
Whelan JT, Kellogg A, Shewchuk BM, et al. (2009) Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression. Journal of Cellular Biochemistry. 107: 992-1001
Hogan KA, Jefferson HS, Karschner VA, et al. (2009) Expression of Pit-1 in nonsomatotrope cell lines induces human growth hormone locus control region histone modification and hGH-N transcription. Journal of Molecular Biology. 390: 26-44
Shewchuk BM, Ho Y, Liebhaber SA, et al. (2006) A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functions. Molecular and Cellular Biology. 26: 6535-46
Shewchuk BM, Liebhaber SA, Cooke NE. (2002) Specification of unique Pit-1 activity in the hGH locus control region. Proceedings of the National Academy of Sciences of the United States of America. 99: 11784-9
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