Amel Dudakovic, Ph.D.
Affiliations: | 2010 | Pharmacology | University of Iowa, Iowa City, IA |
Area:
Pharmacology, OncologyGoogle:
"Amel Dudakovic"Parents
Sign in to add mentor| Raymond J. Hohl | grad student | 2010 | University of Iowa | |
| (Geranylgeranyl diphosphate synthase as a novel cancer therapeutic target.) | ||||
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Publications
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| Carrasco ME, Thaler R, Nardocci G, et al. (2023) Inhibition of Ezh2 redistributes bivalent domains within transcriptional regulators associated with WNT and Hedgehog pathways in osteoblasts. The Journal of Biological Chemistry. 105155 |
| Galvan ML, Paradise CR, Kubrova E, et al. (2021) Multiple pharmacological inhibitors targeting the epigenetic suppressor enhancer of zeste homolog 2 (Ezh2) accelerate osteoblast differentiation. Bone. 150: 115993 |
| Dudakovic A, Samsonraj RM, Paradise CR, et al. (2020) Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. The Journal of Biological Chemistry |
| Sterner RM, Kremer KN, Dudakovic A, et al. (2018) Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. Journal of Immunology (Baltimore, Md. : 1950) |
| Carpio LR, Bradley EW, McGee-Lawrence ME, et al. (2016) Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling. Science Signaling. 9: ra79 |
| Kremer KN, Dudakovic A, Hess AD, et al. (2015) Histone deacetylase inhibitors target the leukemic microenvironment by enhancing a Nherf1-Protein Phosphatase 1α-TAZ signaling pathway in osteoblasts. The Journal of Biological Chemistry |
| Dudakovic A, Camilleri ET, Xu F, et al. (2015) Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2. The Journal of Biological Chemistry |
| Dudakovic A, Camilleri ET, Lewallen EA, et al. (2015) Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells. Journal of Cellular Physiology. 230: 52-62 |
| Dudakovic A, Evans JM, Li Y, et al. (2013) Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation. The Journal of Biological Chemistry. 288: 28783-91 |
| Wasko BM, Dudakovic A, Hohl RJ. (2011) Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate. The Journal of Pharmacology and Experimental Therapeutics. 337: 540-6 |