Melanie I. Herscovitch, Ph.D.
Affiliations: | 2010 | Boston University, Boston, MA, United States |
Area:
Molecular Biology, BiochemistryGoogle:
"Melanie Herscovitch"Parents
Sign in to add mentorThomas D. Gilmore | grad student | 2010 | Boston University | |
(Disulfide bond formation in the nuclear factor-kappaB essential modulator and gene expression profiling of a human B-lymphoma cell line expressing an activated REL transcription factor.) |
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Publications
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Cote SM, Gilmore TD, Shaffer R, et al. (2013) Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity. Biochemistry. 52: 9141-54 |
Thompson RC, Herscovitch M, Zhao I, et al. (2011) NF-κB down-regulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway Journal of Biological Chemistry. 286: 1675-1682 |
Chin M, Herscovitch M, Zhang N, et al. (2009) Overexpression of an activated REL mutant enhances the transformed state of the human B-lymphoma BJAB cell line and alters its gene expression profile. Oncogene. 28: 2100-11 |
Herscovitch M, Comb W, Ennis T, et al. (2008) Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochemical and Biophysical Research Communications. 367: 103-8 |
Gilmore TD, Herscovitch M. (2006) Inhibitors of NF-κB signaling: 785 and counting Oncogene. 25: 6887-6899 |