Neil Segil
Affiliations: | Genetic, Molecular, and Cell Biology | University of Southern California, Los Angeles, CA, United States |
Area:
Cell Biology, Molecular Biology, Neuroscience BiologyGoogle:
"Neil Segil"Children
Sign in to add trainee| Litao Tao | grad student | 2014 | USC |
| Patricia M. White | post-doc | 2000-2008 | House Ear Institute, Los Angeles (Neurotree) |
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Publications
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| Wang X, Llamas J, Trecek T, et al. (2023) SoxC transcription factors shape the epigenetic landscape to establish competence for sensory differentiation in the mammalian organ of Corti. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301301120 |
| Nguyen JD, Llamas J, Shi T, et al. (2023) DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300839120 |
| Sarkar A, Liu NQ, Magallanes J, et al. (2023) STAT3 promotes a youthful epigenetic state in articular chondrocytes. Aging Cell. e13773 |
| Shi T, Beaulieu MO, Saunders LM, et al. (2023) Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes. Elife. 12 |
| Iyer AA, Hosamani I, Nguyen JD, et al. (2022) Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals. Elife. 11 |
| Tao L, Segil N. (2022) CDK2 regulates aminoglycoside-induced hair cell death through modulating c-Jun activity: Inhibiting CDK2 to preserve hearing. Frontiers in Molecular Neuroscience. 15: 1013383 |
| Jen HI, Singh S, Tao L, et al. (2022) GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor. Scientific Reports. 12: 7793 |
| Tao L, Yu HV, Llamas J, et al. (2021) Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration. Developmental Cell |
| Yu HV, Tao L, Llamas J, et al. (2021) POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Kastan N, Gnedeva K, Alisch T, et al. (2021) Small-molecule inhibition of Lats kinases may promote Yap-dependent proliferation in postmitotic mammalian tissues. Nature Communications. 12: 3100 |