Xianxin Hua
Affiliations: | Cell and Molecular Biology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Cell Biology, OncologyGoogle:
"Xianxin Hua"Children
Sign in to add trainee| Robert W. Schnepp | grad student | 2006 | Penn |
| Austin T. Thiel | grad student | 2012 | Penn |
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Publications
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| Nyul TE, Beyries K, Hojnacki T, et al. (2023) Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription. Cancers. 15 |
| Katona BW, Hojnacki T, Glynn RA, et al. (2020) Menin-mediated repression of glycolysis in combination with autophagy protects colon cancer against small molecule EGFR inhibitors. Molecular Cancer Therapeutics |
| He X, Feng Z, Ma J, et al. (2020) Bi-specific and Split CAR T Cells Targeting CD13 and TIM3 Eradicate Acute Myeloid Leukemia. Blood |
| Ma J, He X, Cao Y, et al. (2019) Islet-Specific Prmt5 Excision Leads to Reduced Insulin Expression and Glucose Intolerance in Mice. The Journal of Endocrinology |
| Wu Y, Doepner M, Hojnacki T, et al. (2019) Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway. American Journal of Cancer Research. 9: 1682-1694 |
| Guo H, Du X, Zhang Y, et al. (2019) Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells (Dayton, Ohio) |
| Katona BW, Glynn RA, Paulosky KE, et al. (2019) Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription. Cancer Research |
| Xing B, Ma J, Jiang Z, et al. (2019) GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells. The Journal of Cell Biology |
| Jiang Z, Xing B, Feng Z, et al. (2019) Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in β Cells. Pancreas |
| Jiang Z, Shi D, Tu Y, et al. (2018) Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes via FOXO1/Menin-Mediated Epigenetic Regulation. Diabetes |