Krysten M. Farjo, Ph.D.

Affiliations: 
2009 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Cell Biology, Evolution and Development Biology, Biochemistry
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"Krysten Farjo"

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Jian-xing Ma grad student 2009 University of Oklahoma Health Sciences Center
 (The role of retinol dehydrogenase 10 in vitamin A metabolism.)
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Publications

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Du M, Phelps E, Balangue MJ, et al. (2017) Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration. Investigative Ophthalmology & Visual Science. 58: 4095-4103
Du M, Martin A, Hays F, et al. (2017) Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. Molecular Vision. 23: 185-197
Vanlandingham PA, Nuno DJ, Quiambao AB, et al. (2017) Inhibition of Stat3 by a Small Molecule Inhibitor Slows Vision Loss in a Rat Model of Diabetic Retinopathy. Investigative Ophthalmology & Visual Science. 58: 2095-2105
Du M, Otalora L, Martin A, et al. (2015) Transgenic Mice Over-Expressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration Through a Retinoid-Independent Mechanism. Molecular and Cellular Biology
Farjo KM, Farjo RA, Halsey S, et al. (2012) Retinol-binding protein 4 induces inflammation in human endothelial cells by an NADPH oxidase- and nuclear factor kappa B-dependent and retinol-independent mechanism. Molecular and Cellular Biology. 32: 5103-15
Longeras R, Farjo K, Ihnat M, et al. (2012) A PEDF-derived peptide inhibits retinal neovascularization and blocks mobilization of bone marrow-derived endothelial progenitor cells. Experimental Diabetes Research. 2012: 518426
Farjo KM, Moiseyev G, Nikolaeva O, et al. (2011) RDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis. Developmental Biology. 357: 347-55
Takahashi Y, Moiseyev G, Chen Y, et al. (2011) An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain. The Febs Journal. 278: 973-87
Farjo KM, Ma JX. (2010) The potential of nanomedicine therapies to treat neovascular disease in the retina. Journal of Angiogenesis Research. 2: 21
Moiseyev G, Nikolaeva O, Chen Y, et al. (2010) Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 17551-6
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