Jeffim N. Kuznetsov, Ph.D.
Affiliations: | 2012 | Biochemistry and Molecular Biology (Medicine) | University of Miami, Coral Gables, FL |
Area:
Biochemistry, Molecular Biology, Molecular Chemistry, OncologyGoogle:
"Jeffim Kuznetsov"Parents
Sign in to add mentor| Julio C. Barredo | grad student | 2012 | University of Miami | |
| (AMPK and Akt differentially regulate the UPR in acute lymphoblastic leukemia: Therapeutic implications.) | ||||
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Publications
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| Durante MA, Rodriguez DA, Kurtenbach S, et al. (2020) Single-cell analysis reveals new evolutionary complexity in uveal melanoma. Nature Communications. 11: 496 |
| Owens DA, Kuznetsov JN, Lopez A, et al. (2020) Abstract 4025: New candidate therapy for BAP1-mutant cancer identified using novel screen Cancer Research. 80: 4025-4025 |
| Kuznetsov JN, Aguero TH, Owens DA, et al. (2019) BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Science Advances. 5: eaax1738 |
| Recker KL, Norton S, Sobh A, et al. (2019) Synthetic Lethal Screen to Identify Molecular Mechanisms that Drive Uveal Melanoma Uf Journal of Undergraduate Research. 21 |
| Owens DA, Kuznetsov JN, Kurtenbach S, et al. (2019) Abstract 5199: A novel role for BAP1 in development and tumor suppression Cancer Research. 79: 5199-5199 |
| Leclerc GM, Leclerc GJ, Kuznetsov JN, et al. (2013) Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts. Plos One. 8: e74420 |
| DeSalvo J, Kuznetsov JN, Du J, et al. (2012) Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia. Molecular Cancer Research : McR. 10: 969-78 |
| Kuznetsov JN, DeSalvo J, Du J, et al. (2012) Abstract 4991: Akt and AMPK modulate UPR activity and determine ER stress-induced cell death in response to 2-DG in ALL Cancer Research. 72: 4991-4991 |
| Leclerc GM, Leclerc GJ, Kuznetsov JN, et al. (2012) Abstract 2736: PIM2 is up-regulated in response to metformin-induced cell death triggered by ER stress/UPR in ALL lymphoblasts Cancer Research. 72: 2736-2736 |
| Kuznetsov JN, Leclerc GJ, Leclerc GM, et al. (2011) AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia. Molecular Cancer Therapeutics. 10: 437-47 |