David N. Frick, PH.D.
Affiliations: | 2000-2010 | Biochemistry and Molecular Biology | New York Medical College, New York, NY, United States |
| 2010- | Chemistry & BIOCHEMISTRY | University of Wisconsin, Milwaukee |
Area:
Biochemistry, Molecular Biology, Virology BiologyGoogle:
"David Frick"Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Maurice J. Bessman | grad student | 1990-1996 | (Physics Tree) |
| Charles C. Richardson | post-doc | (Chemistry Tree) |
Collaborators
Sign in to add collaborator| Karyn M. Frick | collaborator | UW-Milwaukee (Neurotree) | |
| Nemanja Vuksanovic | collaborator | (Chemistry Tree) |
BETA: Related publications
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Publications
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| Belayet JB, Beamish S, Rahaman M, et al. (2022) Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice. Journal of Medicinal Chemistry |
| Virdi RS, Bavisotto RV, Hopper NC, et al. (2020) Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. Slas Discovery : Advancing Life Sciences R & D. 2472555220960428 |
| Frick DN, Virdi RS, Vuksanovic N, et al. (2020) Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3. Biochemistry |
| Ray A, Frick DN. (2020) Fluorescent probe displacement assays reveal unique nucleic acid binding properties of human nudix enzymes. Analytical Biochemistry. 595: 113622 |
| Corby MJ, Raicu V, Frick DN. (2018) New Techniques to Study Intracellular Receptors in Living Cells: Insights Into RIG-I-Like Receptor Signaling. Advances in Experimental Medicine and Biology |
| Yerukhimovich MM, Marohnic CC, Frick DN. (2018) Role of the Conserved DECH-box Cysteine in Coupling Hepatitis C Virus Helicase-catalyzed ATP hydrolysis to RNA Unwinding. Biochemistry |
| Corby MJ, Stoneman MR, Biener G, et al. (2017) Quantitative Micro-Spectroscopic Imaging Reveals Viral and Cellular RNA Helicase Interactions in Live Cells. The Journal of Biological Chemistry |
| Bassetto M, Leyssen P, Neyts J, et al. (2017) Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV. Bioorganic & Medicinal Chemistry Letters |
| Bassetto M, Ferla S, Leyssen P, et al. (2016) Novel symmetrical phenylenediamines as potential anti-hepatitis C virus agents. Antiviral Chemistry & Chemotherapy |
| Bassetto M, Leyssen P, Neyts J, et al. (2016) In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase. European Journal of Medicinal Chemistry. 125: 1115-1131 |