Zhong-Yin Zhang
Affiliations: | Biochemistry and Molecular Biology | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Biochemistry, Analytical Chemistry, Molecular BiologyGoogle:
"Zhong-Yin Zhang"Children
Sign in to add trainee| Jinpeng Sun | grad student | 2001-2006 | (Neurotree) |
| Chad D. Walls | grad student | 2012 | Indiana University |
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Publications
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| Chen H, Bai Y, Kobayashi M, et al. (2023) PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation. Molecular Cancer Research : McR |
| Dong J, Miao J, Miao Y, et al. (2023) Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. Angewandte Chemie (International Ed. in English). e202303818 |
| Bai Y, Yu G, Zhou HM, et al. (2022) PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Autophagy. 1-20 |
| Zhu P, Wu X, Zhang RY, et al. (2022) An Integrated Proteomic Strategy to Identify SHP2 Substrates. Journal of Proteome Research |
| Gebregiworgis T, Kano Y, St-Germain J, et al. (2021) The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nature Communications. 12: 6274 |
| Krabill AD, Zhang ZY. (2021) Functional interrogation and therapeutic targeting of protein tyrosine phosphatases. Biochemical Society Transactions. 49: 1723-1734 |
| Xu YF, Chen X, Yang Z, et al. (2021) PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Reports. e52141 |
| Chen H, Libring S, Ruddraraju KV, et al. (2020) SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer. Oncogene |
| Zhu G, Xie J, Kong W, et al. (2020) Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation. Cell |
| Li Q, Bai Y, Lyle LT, et al. (2020) Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America |