David J. Kemble, Ph.D.

Affiliations: 
2009 University of Rhode Island, Providence, RI, United States 
Area:
Molecular Biology, Biochemistry, Oncology
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"David Kemble"

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Gongqin Sun grad student 2009 University of Rhode Island
 (A biochemical study on the regulation of the Src and FGFR family of protein tyrosine kinases.)
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Publications

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Chen L, Marsiglia WM, Chen H, et al. (2020) Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation. Nature Chemical Biology
Kemble DJ, Whitby FG, Robinson H, et al. (2013) Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. The Journal of Biological Chemistry. 288: 10188-94
Sun G, Kemble DJ. (2009) To C or not to C: direct and indirect redox regulation of Src protein tyrosine kinase. Cell Cycle (Georgetown, Tex.). 8: 2353-5
Kemble DJ, Sun G. (2009) Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation. Proceedings of the National Academy of Sciences of the United States of America. 106: 5070-5
Kemble DJ, Wang YH, Sun G. (2006) Bacterial expression and characterization of catalytic loop mutants of SRC protein tyrosine kinase. Biochemistry. 45: 14749-54
Lee S, Ayrapetov MK, Kemble DJ, et al. (2006) Docking-based substrate recognition by the catalytic domain of a protein tyrosine kinase, C-terminal Src kinase (Csk). The Journal of Biological Chemistry. 281: 8183-9
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