Tina M. Cairns, Ph.D.
Affiliations: | 2000 | Pennsylvania State University, State College, PA, United States |
Area:
Microbiology Biology, Molecular BiologyGoogle:
"Tina Cairns"Parents
Sign in to add mentor| Rebecca C. Craven | grad student | 2000 | Penn State | |
| (Rous sarcoma virus structural proteins: Genetic evidence for complex activities in replication.) | ||||
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Publications
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| Atanasiu D, Saw WT, Cairns TM, et al. (2023) Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion. Viruses. 15 |
| Gandy LA, Canning AJ, Lou H, et al. (2022) Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate. Frontiers in Molecular Biosciences. 9: 1043713 |
| Atanasiu D, Saw WT, Cairns TM, et al. (2021) Using Split Luciferase Assay and anti-HSV Glycoprotein Monoclonal Antibodies to Predict a Functional Binding Site Between gD and gH/gL. Journal of Virology |
| Brooks BD, Closmore A, Yang J, et al. (2020) Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition. Molecules (Basel, Switzerland). 25 |
| Cairns TM, Connolly SA. (2020) Entry of Alphaherpesviruses. Current Issues in Molecular Biology. 41: 63-124 |
| Cairns TM, Atanasiu D, Saw WT, et al. (2020) Localization of the interaction site of herpes simplex virus glycoprotein D (gD) on the membrane fusion regulator, gH/gL. Journal of Virology |
| Tuzmen C, Cairns TM, Atanasiu D, et al. (2020) Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies. Molecular Therapy. Methods & Clinical Development. 16: 145-154 |
| Awasthi S, Hook LM, Swaminathan G, et al. (2019) Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants. Vaccine |
| Cairns TM, Ditto NT, Atanasiu D, et al. (2019) Surface plasmon resonance (SPR) reveals direct binding of HSV glycoproteins gH/gL to gD and locates a gH/gL binding site on gD. Journal of Virology |
| Atanasiu D, Saw WT, Lazear E, et al. (2018) Using antibodies and mutants to localize the presumptive gH/gL binding site on HSV gD. Journal of Virology |