Tina M. Cairns, Ph.D.

Affiliations: 
2000 Pennsylvania State University, State College, PA, United States 
Area:
Microbiology Biology, Molecular Biology
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"Tina Cairns"

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Rebecca C. Craven grad student 2000 Penn State
 (Rous sarcoma virus structural proteins: Genetic evidence for complex activities in replication.)
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Publications

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Atanasiu D, Cairns TM. (2024) Special Issue: Research on Herpes Virus Fusion and Entry. Viruses. 16
González-Del Pino GL, Walsh RM, Atanasiu D, et al. (2024) Allosteric mechanism of membrane fusion activation in a herpesvirus. Biorxiv : the Preprint Server For Biology
Atanasiu D, Saw WT, Cairns TM, et al. (2023) Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion. Viruses. 15
Gandy LA, Canning AJ, Lou H, et al. (2022) Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate. Frontiers in Molecular Biosciences. 9: 1043713
Atanasiu D, Saw WT, Cairns TM, et al. (2021) Using Split Luciferase Assay and anti-HSV Glycoprotein Monoclonal Antibodies to Predict a Functional Binding Site Between gD and gH/gL. Journal of Virology
Brooks BD, Closmore A, Yang J, et al. (2020) Characterizing Epitope Binding Regions of Entire Antibody Panels by Combining Experimental and Computational Analysis of Antibody: Antigen Binding Competition. Molecules (Basel, Switzerland). 25
Cairns TM, Connolly SA. (2020) Entry of Alphaherpesviruses. Current Issues in Molecular Biology. 41: 63-124
Cairns TM, Atanasiu D, Saw WT, et al. (2020) Localization of the interaction site of herpes simplex virus glycoprotein D (gD) on the membrane fusion regulator, gH/gL. Journal of Virology
Tuzmen C, Cairns TM, Atanasiu D, et al. (2020) Point Mutations in Retargeted gD Eliminate the Sensitivity of EGFR/EGFRvIII-Targeted HSV to Key Neutralizing Antibodies. Molecular Therapy. Methods & Clinical Development. 16: 145-154
Awasthi S, Hook LM, Swaminathan G, et al. (2019) Antibody responses to crucial functional epitopes as a novel approach to assess immunogenicity of vaccine adjuvants. Vaccine
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